Elettra 2.0: New Structural Biology Opportunities

Session

Session 1 Macromolecular Crystallography Chair: Michele Cianci (Università Politecnica delle Marche)

Chairman: Michele Cianci, Università Politecnica delle MArche

Jul 3, 2023, 9:20 AM

AREA Science Park

1. Elettra 2.0 project and IVU beamlines

Maurizio Polentarutti (Elettra Sincrotrone Trieste)

7/3/23, 9:20 AM

After 27 years of successfully serving the user community, Elettra is undertaking a major upgrade towards a diffraction limited light source, called Elettra 2.0, enabling new science and the development of new technologies to the general benefit.

Due to a substantial reduction of the emittance of the stored electron beam, the new machine will be able to host in particular also in-vacuum...

2. The new MX beamline at Elettra 2.0: μXRD

Nicola Demitri (Elettra Sincrotrone Trieste)

7/3/23, 9:40 AM

The new high brilliance microfocus μXRD beamline will be presented. μXRD aims to fullfill the needs of current XRD2 community and will open new opportunities to Elettra MX users.

23. Combining visual and X-ray sample characterization information in design of macromolecular crystallography experiments

Martin Savko (SOLEIL)

7/3/23, 10:00 AM

The best thing one can do to determine the structure of a biological macromolecule at atomic resolution is to grow a large homogeneous crystal of it, then probe it with flat X-ray beam of the matching size, while rotating it using a perfect goniometer while measuring the complete reciprocal image of its electronic density with a perfect detector.

Though this ideal is not feasible in...

4. New opportunities for time resolved serial crystallography experiments at 4th generation synchrotrons

Daniele de Sanctis (ESRF)

7/3/23, 11:00 AM

22. Infrastructure requirements for running high-throughput crystallographic fragment screening

Ailsa Powell (Diamond Light Source)

7/3/23, 11:30 AM

i04-1 at Diamond Light Source is a fixed wavelength, high throughput beamline, dedicated to running unattended data collection queues. We utilise the beamtime to run XChem fragment screening experiments for both industry and academic users, allowing us on average to collect 2000 samples per week. In addition to what we require from the beamline, this talk will focus on the infrastructure...

12. IT integration with Elettra facility upgrades

Roberto Pugliese (Elettra)

7/3/23, 12:00 PM