Description
A new facility for cryoEM will soon be available in Trieste. Introduction to its future capabilities and perspective from other facilities in Europe will be presented.
Presentation materials
Integrated structural biology aims to provide high-resolution structural information about biological molecules and their complexes in isolated form or in biological context based on data obtained by various experimental and theoretical methods. This helps to understand biological processes and enables drug and vaccine discovery and other applications in biotechnology. For atomic resolution...
Cryo Electron Microscopy (cryo-EM) has revolutionized structure biology, allowing direct visualization of entire molecular machines at atomic resolution. In this talk, I will outline some of the applications of single-particle cryo-EM analysis we use in the lab to investigate the structure and function of enzymes operating in human DNA replication and repair.
We review the current progress and challenges in the field of Machine Learning for Structural Biology. We will discuss existing machine learning algorithms such as AlphaFold for structural prediction, the use of large language models for protein design, and generative models applied to protein-protein docking. The aim of the seminar will be to encourage experts from relevant communities to...
